Transdermal ยท Steady-release ยท Trusted by 110,247+
It was never about willpower.
A patch the size of a quarter. Steady micro-dosing through the skin, hour after hour. 110,247 customers globally have stopped fighting their own chemistry on willpower alone.
Three patches. Three problems.
Pick the patch built for what's kicking your week.
Sleep Skins
For 3am wired-tired. Steady release, no melatonin.
$59.95One month ยท 30 patches
See Sleep โ
Appetite Skins
Ozempic-curious without the needle. Steady, all day.
From $34.9530-day money-back guarantee
See Appetite โ
Energy Skins
Coffee stopped working. Steady release, no crash.
From $151-pack starts here ยท 6 designs
See Energy โTrusted by US clinicians
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110,247+
Customers globally
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4.8โ
Verified-buyer rating
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5ร5 cm
2ร2 in patch ยท sized for real dose
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30 days
Money-back guarantee
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Free
Worldwide shipping
Tired isn't a personality. It's a chemistry problem.
Pick the one that sounds like you. Skip ahead to the patch built for it.
โIn bed at 11. Still staring at the ceiling at 3.โ
You're tired. You know you're tired. But your body didn't get the memo. Sleep Skins release a steady, low-dose blend through the skin overnight.
Show me Sleep Skins โโOzempic results, without the needle.โ
You're not failing. You're fighting your own biology without the right support. Appetite Skins are a transdermal alternative.
Show me Appetite Skins โโFour cups in. Still tired. Still foggy.โ
Energy Skins deliver micro-doses through the skin steadily through the day. No spike. No 2pm crash.
Show me Energy Skins โโI can't slow down. But I can't keep going.โ
Steady release, no jitter, no crash โ for the days you have to actually be on.
Show me Energy Skins โโSame body, different rules.โ
Perimenopause didn't come with an instruction manual. One patch a day. Stick on. Get on with it.
See all Skins โWhy patches ยท Why ours ยท Why Endorfix
The science behind every Skin.
Same delivery system across Sleep, Appetite and Energy. Different actives. Same uncompromising approach.
01 ยท Why patches
Most of what you swallow doesn't make it.
An oral supplement has to survive stomach acid, the small intestine, and what your liver does first. For many oral compounds, what reaches your bloodstream sits in the 10โ20% range.
Transdermal delivery sidesteps that route entirely. The actives go straight through the skin into circulation, micro-dosed steadily over hours instead of dumped in one hit and burned off in one.
Other wellness patches are too small to do anything.
A patch is a reservoir. The amount of active ingredient it can hold is bounded by surface area. Most wellness patches in market are 2 ร 2 cm (0.8 ร 0.8 in) or smaller. We sized ours up.
Appetite & Sleep
5ร5 cm ยท 2ร2 in. 25 cmยฒ of dose-loaded reservoir.
Energy
3ร3 cm ยท 1.2ร1.2 in. 9 cmยฒ โ calibrated for daytime micro-dosing.
Typical wellness patch
4 cmยฒ. Not enough surface area to carry a real dose.
No proprietary blends. No hiding.
Every Endorfix patch is lab-tested and ships from an ISO 13485-certified, FDA-registered medical-device facility. Each formula is built around the goal โ calming actives in Sleep, appetite-regulating actives in Appetite, energy-supporting actives in Energy. Full ingredient list with function on every PDP.
Honokiol
18 mgCalming compound from magnolia bark. Supports a steady stress response without sedation.
Valerenic Acid
12 mgFrom valerian root. Reduces sleep onset latency โ the time it takes to fall asleep.
Oleamide
8 mgNaturally produced fatty acid amide. Supports the body's own deep-rest signalling.
Magnolol
6 mgSister compound to Honokiol from magnolia bark. Works alongside it for stronger stress balance.
Apigenin
6 mgThe active in chamomile that does the actual calming work โ in concentrated form. Supports cortisol recovery.
ฮฒ-Caryophyllene
3 mgTargets the body's CB2 pathway to ease tension. Found naturally in black pepper, cloves, hops.
Statements describe ingredient origins, traditional context and reported effects. They have not been evaluated by the FDA. Endorfix products are not intended to diagnose, treat, cure or prevent any disease.
What clinicians say
Real doctors. Real practices. Real reviews.
Built by an operator who's been here before.
My first company, Glow Dreaming, helped over 250,000 families fix their kids' sleep. I ran it for 8 years before selling to private equity.
Endorfix exists for the same reason. The world is hard enough; if a small thing can take one piece of the load off your day, it deserves to be made.
Frequently Asked Questions
Sleep and Appetite patches release for 10โ12 hours. Energy patches are calibrated for 6โ8 hours. Apply once and forget about it.
Most people feel the patch within 20โ30 minutes of applying. Sleep takes a little longer to fully recalibrate โ the deeper benefits build across the first 5 nights of every 7. Consistency builds the effect.
Inner forearm, upper arm, shoulder, or stomach. Clean, dry skin. Avoid hairy areas. Skin should not be broken or irritated.
The patches are water-resistant, not waterproof. Showering is fine. We don't recommend swimming โ prolonged submersion can lift the adhesive.
No. Once the patch is removed, it's done. The adhesive is single-use and the active delivery has already started. Apply a fresh one.
An oral supplement has to survive stomach acid, the small intestine and your liver before reaching your bloodstream โ most loses 80โ90% of its dose along the way. Transdermal delivery skips that path. The actives go directly through the skin and into circulation, micro-dosed steadily over hours.
If you take prescription medication โ especially GLP-1 drugs, antidepressants, blood-pressure or sleep medication โ please show the ingredient list to your doctor before using. Endorfix is not intended to replace any prescribed treatment.
Designed in Australia. Manufactured at an ISO 13485-certified, FDA-registered medical-device facility โ stricter than supplement-industry GMP. Patches are vegan, latex-free, and use medical-grade pressure-sensitive adhesive suitable for sensitive skin. Formulas are lab-tested on a regular basis.
30-day money-back guarantee. Email us, we refund. No need to send patches back โ hygiene reasons.
Yes. Free shipping worldwide. We made it that way because cost shouldn't be a barrier. We have local fulfilment centres in the US and Canada and a global fulfilment centre serving the rest of the world.
Still have a question?
Reply to any email from us, or send us a note โ typical response within a few hours during business hours.